This text describes how bacteria of the genus Vibrio are common agents of disease in farmed shrimp, especially Penaeus vannamei. Vibrio-related diseases include several conditions affecting different organs and functions of shrimp, such as hepatopancreatic necrosis and white tail syndrome. White tail disease, also called muscle necrosis, affects both freshwater and marine shrimp and is characterized by progressive muscle degeneration without the presence of microorganisms, indicating a sterile and idiopathic origin. Furthermore, white tail syndrome can be confused with viral or bacterial diseases and is related to red disease syndrome (BRS), which can be triggered by various factors, including fungal toxins, lime use, and Vibrio bacteria.